Methyl Detox Profile
Why get profiled?
The Methyl Detox Profile tests critical genes in the methylation pathway. The methylation pathway is the major part of detoxification and the metabolic cycle. More than 50% of people are affected by genetic variations in the methylation pathway 1-3. This profile enables you to intelligently use nutritional supplementation based on your genetics. The Methyl Detox Profile gives comprehensive insights into the functional status of 3 major genes associated with the methionine/homocysteine cycle. A Methyl Detox Profile may benefit you if you are experiencing any of the following:
The MTHFR gene’s purpose is to produce the important MTHFR enzyme in the body. This enzyme is an important part of maintaining optimal health. If the MTHFR gene has a mutation, folate metabolism can be negatively impacted. Improper folate metabolism is implicated in many different diseases.
The MTRR gene codes for the important enzyme, methionine synthase reductase (MSR). Methionine synthase reductase is required for the proper function of methionine synthase (see MTR). Both genes act together to convert homocysteine to methionine. Mutations can be involved with the development of cancers, Parkinson’s disease, depression, hypertension and many others.
AHCY is the only enzyme known to convert S-Adenosylhomocysteine (AdoHcy) to homocysteine. It is crucial that AHCY immediately converts AdoHcy to homocysteine and adenine in order to maintain optimal methylation potential. Studies show a link between mutations in this gene with poor methylation potential and severe myopathies, developmental delays and hypermethioninemia.
MTR codes for the enzyme, methionine synthase (MS). MS converts homocysteine to methionine using methylated vitamin B12. Mutations in this gene significantly impact homocysteine metabolism, which can increase the risk for a number of chronic conditions such as cardiovascular diseases, metabolic and neurological conditions and certain cancers.
COMT is the major gene involved in methylation. It plays an important role in a variety of disorders, including estrogen-induced cancers, Parkinson’s disease, depression, hypertension and many others. COMT is also necessary for maintaining the proper balance of neurotransmitters with SAMe obtained from methionine. Genetic mutations in COMT can result in various neurological problems and has also been associated with Autism.
Homocysteine is an amino acid that is involved in maintaining the methionine cycle. Elevated homocysteine levels are well-known risk factors for chronic disease, particularly cardiovascular, diabetes and neurodegenerative disorders.
The kit will be shipped containing the necessary supplies within 3 business days. We will request a phlebotomist to contact you for scheduling of your blood draw at a time and location convenient for you.
See what people are saying
I am so happy I decided to change my life and schedule an appointment with Helen. She has truly helped change my whole mindset. She’s taught me to stick to better sleep, and an eating schedule to get my metabolism running. With just a few tweaks to my schedule and enjoying eating my food instead of skipping meals, I’ve boosted my metabolism and lost 19lbs in 1 month! I’m so grateful to Helen and excited I finally found a lifestyle change that will last forever.
As soon as I met Helen I knew I made a life-changing choice. I have been struggling with losing a few pounds and trying to figure out what to eat for optimal health benefits. From my first visit, I knew I was on my way to a healthier me. Helen has educated me in several areas. Most importantly, learning how to fuel my body nutritiously. She also introduced me to an exercise program that fits my fitness level.
I recently began using Helen’s app that helps with meal planning. Helen created a nutrition prescription for me and the app gives menu options for breakfast, snacks, lunch and dinner. These are healthy choices that are easy and delicious. If there is something on the menu I do not find appealing, I am able to swap out the meal for other options. This app makes it easy to try new and different combinations of energizing food.
Helen has helped bring exciting variety to my meals. I am so grateful to have the expertise of Helen guiding me to a healthier lifestyle.
When it comes to meal planning, the app has been a game-changer! I can plan simple meals and snacks, and even swap out foods if I wish. By tracking my food choices, water intake, and exercise on a daily log within the app, I can hold myself accountable for the goals I have set for myself. The grocery list feature allows me to add any ingredients I need right into my Instacart app with a click and my meals are planned and shopped for!! So convenient.
I have been pleasantly surprised with the app and Helen’s input when it comes to making weeknights a little less hectic, and a little healthier!
Realizing you have an eating disorder is one thing, admitting it is another. Doing something about it can seem overwhelming. When you have help along the recovery route, it becomes manageable and you can begin to unlearn the old habits and replace them with better ones. My focus had always been on weight, exercise and calories at the expense of nutrition. Once I was ready to start addressing it, Helen helped me break things down into small digestible steps that I can learn one at a time. In less than two months my back pain has improved, my body and mind feel better and while I still have a lot to learn, the difference I’ve noticed in six weeks is remarkable. Helen doesn’t use the word diet. Rather, she focuses on your individual needs and helps you address things one by one. I’m grateful to have her guide the nutrition side of my recovery.
Although my goal is weight loss, Helen has an attitude and approach that doesn’t make me feel judged, outcasted, or downgraded. Her focus is on healthy lifestyle changes and not the number on the scale. I lost my first 20 lbs in less than 3 months, even with numerous celebration and parties. Helen encouraged me to have fun and enjoy my time. It makes what she teaches you realistic. This isn’t a fad diet. It is a new way of life and a reasonable one!
During high school, I was a three-sport athlete and I went from working out 5 to 7 days a week to starting college and living away from home during the pandemic. I found myself not having access to a gym or healthy meals and it resulted in weight gain and stress. Helen helped me set achievable goals and balance nutrition and exercise. I have more energy, lost the weight I had gained, and feel good about myself again.
I have made it to the gym 3 days in a row. One day my husband came also. I am trying Helen’s recipes and have decided to cook ahead on Saturday. Thank you for helping me reach my goals and as you say, “It is for me and my health”…I do feel better over all! I share what I have learned with others. And people are coming out of the wood work, coming up to me saying what a change they see in me. I am looking forward to wearing shorts this summer. I haven’t worn any for 3 yrs…. just capri’s!