Why get profiled?

The Methyl Detox Profile tests critical genes in the methylation pathway. The methylation pathway is the major part of detoxification and the metabolic cycle.  More than 50% of people are affected by genetic variations in the methylation pathway 1-3.  This profile enables you to intelligently use nutritional supplementation based on your genetics.  The Methyl Detox Profile gives comprehensive insights into the functional status of 3 major genes associated with the methionine/homocysteine cycle.  A Methyl Detox Profile may benefit you if you are experiencing any of the following:

Z
Cardiovascular Diseases
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Musculoskeletal Disorders
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Neurological Disorders
Z
Eye Diseases
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Metabolic Conditions
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Cancer

Methyl Detox Profile Pricing & Contents

Advanced 1

$350

N

MTHFR

N

MTR

N

MTRR

N

COMT

N

AHCY

N

Homocysteine

Advanced 2 (Genetic Only)

$300

N

MTHFR

N

MTR

N

MTRR

N

COMT

N

AHCY

N

Homocysteine

Basic

$250

N

MTHFR

N

MTR

N

COMT

N

Homocysteine

N

MTRR

N

AHCY

All blood draw services are handled with accredited and licensed 3rd party companies. We are not responsible for scheduling, drawing, handling or shipment back to the Cell Science laboratory.
Saliva test optional

Test Components

MTHFR

The MTHFR gene’s purpose is to produce the important MTHFR enzyme in the body. This enzyme is an important part of maintaining optimal health. If the MTHFR gene has a mutation, folate metabolism can be negatively impacted. Improper folate metabolism is implicated in many different diseases.

MTRR

The MTRR gene codes for the important enzyme, methionine synthase reductase (MSR). Methionine synthase reductase is required for the proper function of methionine synthase (see MTR). Both genes act together to convert homocysteine to methionine. Mutations can be involved with the development of cancers, Parkinson’s disease, depression, hypertension and many others.

AHCY

AHCY is the only enzyme known to convert S-Adenosylhomocysteine (AdoHcy) to homocysteine. It is crucial that AHCY immediately converts AdoHcy to homocysteine and adenine in order to maintain optimal methylation potential. Studies show a link between mutations in this gene with poor methylation potential and severe myopathies, developmental delays and hypermethioninemia.

MTR

MTR codes for the enzyme, methionine synthase (MS). MS converts homocysteine to methionine using methylated vitamin B12. Mutations in this gene significantly impact homocysteine metabolism, which can increase the risk for a number of chronic conditions such as cardiovascular diseases, metabolic and neurological conditions and certain cancers.

COMT

COMT is the major gene involved in methylation. It plays an important role in a variety of disorders, including estrogen-induced cancers, Parkinson’s disease, depression, hypertension and many others. COMT is also necessary for maintaining the proper balance of neurotransmitters with SAMe obtained from methionine. Genetic mutations in COMT can result in various neurological problems and has also been associated with Autism.

Homocysteine

Homocysteine is an amino acid that is involved in maintaining the methionine cycle. Elevated homocysteine levels are well-known risk factors for chronic disease, particularly cardiovascular, diabetes and neurodegenerative disorders.

When purchasing your test expect the following:
The kit will be shipped containing the necessary supplies within 3 business days. We will request a phlebotomist to contact you for scheduling of your blood draw at a time and location convenient for you.

See what people are saying

Realizing you have an eating disorder is one thing, admitting it is another.  Doing something about it can seem overwhelming.  When you have help along the recovery route, it becomes manageable and you can begin to unlearn the old habits and replace them with better ones.  My focus had always been on weight, exercise and calories at the expense of nutrition.  Once I was ready to start addressing it, Helen helped me break things down into small digestible steps that I can learn one at a time.  In less than two months my back pain has improved, my body and mind feel better and while I still have a lot to learn, the difference I’ve noticed in six weeks is remarkable. Helen doesn’t use the word diet.  Rather, she focuses on your individual needs and helps you address things one by one.  I’m grateful to have her guide the nutrition side of my recovery.


Dave E, age 34

Although my goal is weight loss, Helen has an attitude and approach that doesn’t make me feel judged, outcasted, or downgraded. Her focus is on healthy lifestyle changes and not the number on the scale. I lost my first 20 lbs in less than 3 months, even with numerous celebration and parties. Helen encouraged me to have fun and enjoy my time. It makes what she teaches you realistic. This isn’t a fad diet.  It is a new way of life and a reasonable one!

 


Christine C age 27

During high school, I was a three-sport athlete and I went from working out 5 to 7 days a week to starting college and living away from home during the pandemic. I found myself not having access to a gym or healthy meals and it resulted in weight gain and stress. Helen helped me set achievable goals and balance nutrition and exercise. I have more energy, lost the weight I had gained, and feel good about myself again.


Emily K age 18

I have made it to the gym 3 days in a row.  One day my husband came also. I am trying Helen’s recipes and have decided to cook ahead on Saturday. Thank you for helping me reach my goals and as you say, “It is for me and my health”…I do feel better over all!  I share what I have learned with others.  And people are coming out of the wood work, coming up to me saying what a change they see in me.  I am looking forward to wearing shorts this summer. I haven’t worn any for 3 yrs…. just capri’s!


Heidi Erie, PA

I cannot express my gratitude enough to Helen Agresti of Professional Nutrition Consulting.

Recently, while at a social gathering, I was talking about the summer and all it will hold this year. Although tiring…the summer was full of activity. Helen smiled warmly and then noticed, as I proceeded to go through my third glass of water…not the water all the ice I was chewing. She mentioned this may be a sign of low iron. Upon her recommendation, I visited my family physician and had blood work done. One week later, the letter arrived. I am indeed anemic and need to start a Iron supplement immediately. Helen has always been a true champion for her clients, but it is also her skillful and comprehensive approach to her work that allows her clients to reach their true potentials. Through casual conversation, she demonstrated how she crosses into all aspects of her expertise…healthy on the inside and outside.

Many many thanks and so much Gratitude!


Michele Erie, PA

Helen has really helped me get the most out of my diet and exercise plan. She taught me to really understand the nutrition label and how to make healthier choices that make a difference. Helen doesn’t use the word “diet” I have learned from her that I am making a lifestyle change. She is easy to work with and has a lot of great ideas to make your favorite meals healthier.


Lisa, Erie, PA

I am so thankful for finding Helen. She has been great in helping me lose weight (over 20 pounds!) but more importantly, helping me learn to live a healthier lifestyle with food and exercise. Helen is very patient and encouraging on this journey. I have learned to read labels better and also the importance of putting the right combination of foods together for sustainable energy. There are no gimmicks or prepackaged foods with Helen. It is about making right choices, eating whole foods and exercising. Thank you, Helen!


Evelyn Titusville, PA

I have never been able to lose weight until I met Helen. She is a great motivator and always has a smile and something good to say to me in a positive way. Before seeing Helen twice a month I ate chips, cookies, crackers and all the quick and fattening foods that are easy to get and a quick fix. I now go to the gym and swim and exercise when before I sat and ate all evening. Now I have lost almost 25 pounds and I feel so much better. To be continued!!


Natalie Erie, PA

Change Your Life Today

Professional Nutrition Consulting provides professional advice by educating clients on their individual nutritional needs. We believe fueling our body with the proper variety and portion of foods at consistent times of the day will lead to a healthier life.