Methyl Detox Profile
Why get profiled?
The Methyl Detox Profile tests critical genes in the methylation pathway. The methylation pathway is the major part of detoxification and the metabolic cycle. More than 50% of people are affected by genetic variations in the methylation pathway 1-3. This profile enables you to intelligently use nutritional supplementation based on your genetics. The Methyl Detox Profile gives comprehensive insights into the functional status of 3 major genes associated with the methionine/homocysteine cycle. A Methyl Detox Profile may benefit you if you are experiencing any of the following:
The MTHFR gene’s purpose is to produce the important MTHFR enzyme in the body. This enzyme is an important part of maintaining optimal health. If the MTHFR gene has a mutation, folate metabolism can be negatively impacted. Improper folate metabolism is implicated in many different diseases.
The MTRR gene codes for the important enzyme, methionine synthase reductase (MSR). Methionine synthase reductase is required for the proper function of methionine synthase (see MTR). Both genes act together to convert homocysteine to methionine. Mutations can be involved with the development of cancers, Parkinson’s disease, depression, hypertension and many others.
AHCY is the only enzyme known to convert S-Adenosylhomocysteine (AdoHcy) to homocysteine. It is crucial that AHCY immediately converts AdoHcy to homocysteine and adenine in order to maintain optimal methylation potential. Studies show a link between mutations in this gene with poor methylation potential and severe myopathies, developmental delays and hypermethioninemia.
MTR codes for the enzyme, methionine synthase (MS). MS converts homocysteine to methionine using methylated vitamin B12. Mutations in this gene significantly impact homocysteine metabolism, which can increase the risk for a number of chronic conditions such as cardiovascular diseases, metabolic and neurological conditions and certain cancers.
COMT is the major gene involved in methylation. It plays an important role in a variety of disorders, including estrogen-induced cancers, Parkinson’s disease, depression, hypertension and many others. COMT is also necessary for maintaining the proper balance of neurotransmitters with SAMe obtained from methionine. Genetic mutations in COMT can result in various neurological problems and has also been associated with Autism.
Homocysteine is an amino acid that is involved in maintaining the methionine cycle. Elevated homocysteine levels are well-known risk factors for chronic disease, particularly cardiovascular, diabetes and neurodegenerative disorders.
When purchasing your test expect the following:
The kit will be shipped containing the necessary supplies within 4-7 business days.
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I HIGHLY recommend Helen Agresti. Within the past month, she’s helped me lose 11 lbs. without having to resort to any fad diet. I’ve been going back and forth with keto for years… I can eat bread now. I’ve had no cravings at all because I’m eating a balanced diet. She’s taught me how to read labels and cut chemicals out of my food. I could go on and on, but I feel so much better and healthier. The money I saved on groceries alone over the past month has already paid for the initial consult. I cannot recommend her enough.
Helen has completely changed the way I look at nutrition and a healthy lifestyle. She has taught me the balance of giving my body what it needs, while also enjoying life at the same time. Helen helped me find a workout routine that works best for me and was sustainable. I am forever grateful for her support and motivation to get me on the right track to feeling my absolute best!
I am so grateful to find Helen. She has help me understand nutrition and how to fuel my body so I don’t feel deprived. She has helped me to understand my portions of food, and given me guidance to understand the value in good wholesome foods. I am down 25 pounds and feeling great! I am so happy to be headed in the right direction.
I am so happy I decided to change my life and schedule an appointment with Helen. She has truly helped change my whole mindset. She’s taught me to stick to better sleep, and an eating schedule to get my metabolism running. With just a few tweaks to my schedule and enjoying eating my food instead of skipping meals, I’ve boosted my metabolism and lost 19lbs in 1 month! I’m so grateful to Helen and excited I finally found a lifestyle change that will last forever.
As soon as I met Helen I knew I made a life-changing choice. I have been struggling with losing a few pounds and trying to figure out what to eat for optimal health benefits. From my first visit, I knew I was on my way to a healthier me. Helen has educated me in several areas. Most importantly, learning how to fuel my body nutritiously. She also introduced me to an exercise program that fits my fitness level.
I recently began using Helen’s app that helps with meal planning. Helen created a nutrition prescription for me and the app gives menu options for breakfast, snacks, lunch and dinner. These are healthy choices that are easy and delicious. If there is something on the menu I do not find appealing, I am able to swap out the meal for other options. This app makes it easy to try new and different combinations of energizing food.
Helen has helped bring exciting variety to my meals. I am so grateful to have the expertise of Helen guiding me to a healthier lifestyle.
When it comes to meal planning, the app has been a game-changer! I can plan simple meals and snacks, and even swap out foods if I wish. By tracking my food choices, water intake, and exercise on a daily log within the app, I can hold myself accountable for the goals I have set for myself. The grocery list feature allows me to add any ingredients I need right into my Instacart app with a click and my meals are planned and shopped for!! So convenient.
I have been pleasantly surprised with the app and Helen’s input when it comes to making weeknights a little less hectic, and a little healthier!
Realizing you have an eating disorder is one thing, admitting it is another. Doing something about it can seem overwhelming. When you have help along the recovery route, it becomes manageable and you can begin to unlearn the old habits and replace them with better ones. My focus had always been on weight, exercise and calories at the expense of nutrition. Once I was ready to start addressing it, Helen helped me break things down into small digestible steps that I can learn one at a time. In less than two months my back pain has improved, my body and mind feel better and while I still have a lot to learn, the difference I’ve noticed in six weeks is remarkable. Helen doesn’t use the word diet. Rather, she focuses on your individual needs and helps you address things one by one. I’m grateful to have her guide the nutrition side of my recovery.