Methyl Detox Profile
Why get profiled?
The Methyl Detox Profile tests critical genes in the methylation pathway. The methylation pathway is the major part of detoxification and the metabolic cycle. More than 50% of people are affected by genetic variations in the methylation pathway 1-3. This profile enables you to intelligently use nutritional supplementation based on your genetics. The Methyl Detox Profile gives comprehensive insights into the functional status of 3 major genes associated with the methionine/homocysteine cycle. A Methyl Detox Profile may benefit you if you are experiencing any of the following:
The MTHFR gene’s purpose is to produce the important MTHFR enzyme in the body. This enzyme is an important part of maintaining optimal health. If the MTHFR gene has a mutation, folate metabolism can be negatively impacted. Improper folate metabolism is implicated in many different diseases.
The MTRR gene codes for the important enzyme, methionine synthase reductase (MSR). Methionine synthase reductase is required for the proper function of methionine synthase (see MTR). Both genes act together to convert homocysteine to methionine. Mutations can be involved with the development of cancers, Parkinson’s disease, depression, hypertension and many others.
AHCY is the only enzyme known to convert S-Adenosylhomocysteine (AdoHcy) to homocysteine. It is crucial that AHCY immediately converts AdoHcy to homocysteine and adenine in order to maintain optimal methylation potential. Studies show a link between mutations in this gene with poor methylation potential and severe myopathies, developmental delays and hypermethioninemia.
MTR codes for the enzyme, methionine synthase (MS). MS converts homocysteine to methionine using methylated vitamin B12. Mutations in this gene significantly impact homocysteine metabolism, which can increase the risk for a number of chronic conditions such as cardiovascular diseases, metabolic and neurological conditions and certain cancers.
COMT is the major gene involved in methylation. It plays an important role in a variety of disorders, including estrogen-induced cancers, Parkinson’s disease, depression, hypertension and many others. COMT is also necessary for maintaining the proper balance of neurotransmitters with SAMe obtained from methionine. Genetic mutations in COMT can result in various neurological problems and has also been associated with Autism.
Homocysteine is an amino acid that is involved in maintaining the methionine cycle. Elevated homocysteine levels are well-known risk factors for chronic disease, particularly cardiovascular, diabetes and neurodegenerative disorders.
The kit will be shipped containing the necessary supplies within 3 business days. We will request a phlebotomist to contact you for scheduling of your blood draw at a time and location convenient for you.
See what people are saying
During high school, I was a three-sport athlete and I went from working out 5 to 7 days a week to starting college and living away from home during the pandemic. I found myself not having access to a gym or healthy meals and it resulted in weight gain and stress. Helen helped me set achievable goals and balance nutrition and exercise. I have more energy, lost the weight I had gained, and feel good about myself again.
I have made it to the gym 3 days in a row. One day my husband came also. I am trying Helen’s recipes and have decided to cook ahead on Saturday. Thank you for helping me reach my goals and as you say, “It is for me and my health”…I do feel better over all! I share what I have learned with others. And people are coming out of the wood work, coming up to me saying what a change they see in me. I am looking forward to wearing shorts this summer. I haven’t worn any for 3 yrs…. just capri’s!
I cannot express my gratitude enough to Helen Agresti of Professional Nutrition Consulting.
Recently, while at a social gathering, I was talking about the summer and all it will hold this year. Although tiring…the summer was full of activity. Helen smiled warmly and then noticed, as I proceeded to go through my third glass of water…not the water all the ice I was chewing. She mentioned this may be a sign of low iron. Upon her recommendation, I visited my family physician and had blood work done. One week later, the letter arrived. I am indeed anemic and need to start a Iron supplement immediately. Helen has always been a true champion for her clients, but it is also her skillful and comprehensive approach to her work that allows her clients to reach their true potentials. Through casual conversation, she demonstrated how she crosses into all aspects of her expertise…healthy on the inside and outside.
Many many thanks and so much Gratitude!
Helen has really helped me get the most out of my diet and exercise plan. She taught me to really understand the nutrition label and how to make healthier choices that make a difference. Helen doesn’t use the word “diet” I have learned from her that I am making a lifestyle change. She is easy to work with and has a lot of great ideas to make your favorite meals healthier.
I am so thankful for finding Helen. She has been great in helping me lose weight (over 20 pounds!) but more importantly, helping me learn to live a healthier lifestyle with food and exercise. Helen is very patient and encouraging on this journey. I have learned to read labels better and also the importance of putting the right combination of foods together for sustainable energy. There are no gimmicks or prepackaged foods with Helen. It is about making right choices, eating whole foods and exercising. Thank you, Helen!
I have never been able to lose weight until I met Helen. She is a great motivator and always has a smile and something good to say to me in a positive way. Before seeing Helen twice a month I ate chips, cookies, crackers and all the quick and fattening foods that are easy to get and a quick fix. I now go to the gym and swim and exercise when before I sat and ate all evening. Now I have lost almost 25 pounds and I feel so much better. To be continued!!
I went to see Helen about losing weight. I’ve tried to lose weight in the past and would lose 4 or 5 pounds and then gain it right back. I’m an unusual client because I work 3rd shift. Helen helped me figure out what I should be eating and when. She also said I would lose 20 pounds in 2 months and I thought she was crazy but before the 2 months was up I had lost 20 lbs. I now realize by eating right and adding some exercise anyone can lose the weight if they set their mind to it. I still have a little farther to go to reach my goal but I know with Helen’s help I will achieve the goal I set out for.
I am down 90 lbs! Helen has helped me improve my eating habits. I now make sure to read labels, and I cut out unhealthy snacking between meals. Along with creating healthy eating habits, I also make sure to go for plenty of walks. Since losing weight, I find that I have more energy and the walks are no longer tiring like they used to be. Over the past few months, I have lowered my blood pressure and my cholesterol. Helen has been a great help, during our consultations, she has provided me with great advice and continued words of encouragement. With Helen’s aid, I have been able to successfully lose weight and keep it off. I really feel great!
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